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Issue 21, 2017
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Reversible conformational changes in the parallel type G-quadruplex structure inside a thermoresponsive hydrogel

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Abstract

The novel property of reversible regulation of parallel type G-quadruplexes with moderate temperature changes was discovered in thermoresponsive hydrogels using a universal chiroptical spectrophotometer 1 (UCS-1). This study is the first to report the regulation of the ssDNA steric structure by using a poly(N-isopropylacrylamide) (PNIPAAm) gel.

Graphical abstract: Reversible conformational changes in the parallel type G-quadruplex structure inside a thermoresponsive hydrogel

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Article information


Submitted
12 Jan 2017
Accepted
22 Feb 2017
First published
22 Feb 2017

Chem. Commun., 2017,53, 3142-3144
Article type
Communication

Reversible conformational changes in the parallel type G-quadruplex structure inside a thermoresponsive hydrogel

E. Hasuike, A. M. Akimoto, R. Kuroda, K. Matsukawa, Y. Hiruta, H. Kanazawa and R. Yoshida, Chem. Commun., 2017, 53, 3142
DOI: 10.1039/C7CC00279C

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