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Issue 13, 2017
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Self-assembly of ultra-small micelles from amphiphilic lipopeptoids

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Abstract

Poly(N-substituted glycine) “peptoids” constitute a promising class of peptide-mimetic materials. We introduce the self-assembly of lipopeptoids into spherical micelles ca. 5 nm in diameter as well as larger assemblies by varying the peptoid sequence design. Our results point to design rules for the self-assembly of peptoid nanostructures, enabling the creation of stable, ultra-small peptidomimetic nanospheres.

Graphical abstract: Self-assembly of ultra-small micelles from amphiphilic lipopeptoids

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Supplementary files

Article information


Submitted
14 Dec 2016
Accepted
25 Jan 2017
First published
25 Jan 2017

This article is Open Access

Chem. Commun., 2017,53, 2178-2181
Article type
Communication

Self-assembly of ultra-small micelles from amphiphilic lipopeptoids

K. H. A. Lau, V. Castelletto, T. Kendall, J. Sefcik, I. W. Hamley, M. Reza and J. Ruokolainen, Chem. Commun., 2017, 53, 2178
DOI: 10.1039/C6CC09888F

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