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Issue 29, 2017
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C-Phycocyanin as a tumour-associated macrophage-targeted photosensitiser and a vehicle of phthalocyanine for enhanced photodynamic therapy

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Abstract

C-Phycocyanin (CPC) as a tumour-associated macrophage (TAM)-targeted photosensitiser has been first proved, and used as a vehicle of zinc phthalocyanine (ZnPc) to fabricate a ZnPc–CPC conjugate, which exhibits an efficient in vitro photodynamic activity, and selectively accumulates in tumour sites probably due to the affinity to TAM.

Graphical abstract: C-Phycocyanin as a tumour-associated macrophage-targeted photosensitiser and a vehicle of phthalocyanine for enhanced photodynamic therapy

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Supplementary files

Article information


Submitted
30 Nov 2016
Accepted
13 Mar 2017
First published
20 Mar 2017

Chem. Commun., 2017,53, 4112-4115
Article type
Communication

C-Phycocyanin as a tumour-associated macrophage-targeted photosensitiser and a vehicle of phthalocyanine for enhanced photodynamic therapy

D. Wan, B. Zheng, M. Ke, J. Duan, Y. Zheng, C. Yeh and J. Huang, Chem. Commun., 2017, 53, 4112
DOI: 10.1039/C6CC09541K

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