Issue 25, 2017
From the journal:

Chemical Communications

A general strategy for the synthesis of homogeneous hyaluronan conjugates and their biological applications†

Xuan Fu,a   Wenjing Shang,a   Shuaishuai Wang,b   Yunpeng Liu,b   Jingyao Qu,a   Xi Chen, ORCID logo c   Peng George Wang*ab  and  Junqiang Fang ORCID logo *a  

* Corresponding authors

a National Glycoengineering Research Center, Shandong Provincial Key Laboratory of Glycochemistry and Glycobiology, Shandong University, Jinan, Shandong 250100, People's Republic of China
E-mail: fangjunqiang@sdu.edu.cn

b Department of Chemistry and Center of Diagnostics & Therapeutics, Georgia State University, 50 Decatur St SE, Atlanta, GA 30303, USA
E-mail: pwang11@gsu.edu

c Department of Chemistry, University of California, One Shields Avenue, Davis, CA 95616, USA

Abstract

Here, we developed a general strategy for synthesizing homogeneous HA conjugates, and generated homogeneous HA–pNP, HA–biotin, and HA–oroxylin conjugates to investigate the relationships between HA chain length and its diverse biological functions.

Graphical abstract: A general strategy for the synthesis of homogeneous hyaluronan conjugates and their biological applications

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Article information

DOI
https://doi.org/10.1039/C6CC09431G
Article type
Communication
Submitted
26 Nov 2016
Accepted
28 Feb 2017
First published
02 Mar 2017

Chem. Commun., 2017,53, 3555-3558

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A general strategy for the synthesis of homogeneous hyaluronan conjugates and their biological applications

X. Fu, W. Shang, S. Wang, Y. Liu, J. Qu, X. Chen, P. G. Wang and J. Fang, Chem. Commun., 2017, 53, 3555 DOI: 10.1039/C6CC09431G

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