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Issue 23, 2017
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Enzyme-responsive reporter molecules for selective localization and fluorescence imaging of pathogenic biofilms

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Abstract

Pathogenic bacteria and their biofilm formation are responsible for a broad spectrum of microbial infections. A novel enzyme-responsive reporter molecule (ERM-1), which can specifically recognize AmpC β-lactamase (Bla) in drug resistant bacteria, has been developed to enable the selective localization of biofilms.

Graphical abstract: Enzyme-responsive reporter molecules for selective localization and fluorescence imaging of pathogenic biofilms

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Publication details

The article was received on 21 Nov 2016, accepted on 22 Dec 2016 and first published on 22 Dec 2016


Article type: Communication
DOI: 10.1039/C6CC09296A
Chem. Commun., 2017,53, 3330-3333

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    Enzyme-responsive reporter molecules for selective localization and fluorescence imaging of pathogenic biofilms

    J. Aw, F. Widjaja, Y. Ding, J. Mu, Y. Liang and B. Xing, Chem. Commun., 2017, 53, 3330
    DOI: 10.1039/C6CC09296A

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