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Issue 7, 2017
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Tumor-cell targeting polydiacetylene micelles encapsulated with an antitumor drug for the treatment of ovarian cancer

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Abstract

Peptide functionalized polydiacetylene (PDA) micelles encapsulated with camptothecin (CPT) kill ovarian cancer cells by the lysosome release of anticancer drug CPT. Moreover, the sub-30 nm PDA micelles penetrate efficiently into a tumor for enhanced therapeutic efficacy.

Graphical abstract: Tumor-cell targeting polydiacetylene micelles encapsulated with an antitumor drug for the treatment of ovarian cancer

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Article information


Submitted
25 Oct 2016
Accepted
05 Dec 2016
First published
20 Dec 2016

Chem. Commun., 2017,53, 1233-1236
Article type
Communication

Tumor-cell targeting polydiacetylene micelles encapsulated with an antitumor drug for the treatment of ovarian cancer

D. Yao, S. Li, X. Zhu, J. Wu and H. Tian, Chem. Commun., 2017, 53, 1233
DOI: 10.1039/C6CC08581D

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