A benzoxazole functionalized fluorescent probe for selective Fe3+ detection and intracellular imaging in living cells

Zheng Yang; Xinxin Bai; Siyue Ma; Xiangrong Liu; Shunsheng Zhao; Zaiwen Yang

doi:10.1039/C6AY02660E

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A benzoxazole functionalized fluorescent probe for selective Fe³⁺ detection and intracellular imaging in living cells†

Zheng Yang,*^ab Xinxin Bai,^a Siyue Ma,^b Xiangrong Liu,^a Shunsheng Zhao^a and Zaiwen Yang^a

Author affiliations

* Corresponding authors

^a School of Chemistry & Chemical Engineering, Xi'an University of Science and Technology, Xi'an, China

^b Ministry of Education Key Laboratory of Synthetic and Natural Functional Molecule Chemistry, College of Chemistry & Materials Science, Northwest University, Xi'an, China

Abstract

A rhodamine based 2-aminobenzoxazole functionalized probe was presented for reversible detection of Fe³⁺ driven by the coordination of Fe³⁺ to 2-aminobenzoxazole that resulted in strong fluorescence emission and color change. Fluorescent imaging in living L929 and MG-63 cells offered a promising candidate for mapping Fe³⁺ in biological samples.

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Article information

DOI: https://doi.org/10.1039/C6AY02660E
Article type: Communication
Submitted: 25 Sep 2016
Accepted: 01 Nov 2016
First published: 08 Nov 2016

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Anal. Methods, 2017,9, 18-22

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A benzoxazole functionalized fluorescent probe for selective Fe³⁺ detection and intracellular imaging in living cells

Z. Yang, X. Bai, S. Ma, X. Liu, S. Zhao and Z. Yang, Anal. Methods, 2017, 9, 18 DOI: 10.1039/C6AY02660E

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Analytical Methods