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Issue 11, 2017
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Taking advantage of the disadvantage: employing the high aqueous instability of amorphous calcium carbonate to realize burst drug release within cancer cells

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Abstract

The high aqueous instability of amorphous calcium carbonate (ACC), which will lead to a burst release of its payload, has generally been recognized as the major obstacle for its further application in nanomedicine. Herein, a locking/unlocking strategy was applied to employ the instability of ACC to realize burst drug release within cancer cells.

Graphical abstract: Taking advantage of the disadvantage: employing the high aqueous instability of amorphous calcium carbonate to realize burst drug release within cancer cells

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Publication details

The article was received on 28 Oct 2016, accepted on 13 Feb 2017 and first published on 14 Feb 2017


Article type: Communication
DOI: 10.1039/C6TB02826H
J. Mater. Chem. B, 2017,5, 2068-2073

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    Taking advantage of the disadvantage: employing the high aqueous instability of amorphous calcium carbonate to realize burst drug release within cancer cells

    C. Wang, S. Chen, Q. Yu, F. Hu and H. Yuan, J. Mater. Chem. B, 2017, 5, 2068
    DOI: 10.1039/C6TB02826H

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