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Issue 47, 2017, Issue in Progress
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Development of a pigment-based whole-cell biosensor for the analysis of environmental copper

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Abstract

Using engineered microorganisms to detect heavy metals in the environment has proven to be highly effective and robust. This paper reports on the development of a novel microbial sensor for the detection of copper ions. To develop this microbial sensor, we screened and characterized various biological parts, including promoters, output signals, and hosts. In addition, we used the plant pigment betaxanthin to output fluorescent signals in order to reduce the detection time. The resulting whole-cell biosensor presented a good sensitivity when detecting copper ions in environmental samples including freshwater pond and tap water.

Graphical abstract: Development of a pigment-based whole-cell biosensor for the analysis of environmental copper

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Publication details

The article was received on 01 Apr 2017, accepted on 26 May 2017 and first published on 05 Jun 2017


Article type: Paper
DOI: 10.1039/C7RA03778C
RSC Adv., 2017,7, 29302-29305
  • Open access: Creative Commons BY license
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    Development of a pigment-based whole-cell biosensor for the analysis of environmental copper

    P. Chen, C. Lin, K. Guo and Y. Yeh, RSC Adv., 2017, 7, 29302
    DOI: 10.1039/C7RA03778C

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