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Issue 46, 2017
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Recent advances in pharmacokinetics approach for herbal medicine

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Abstract

Traditional Chinese Medicine (TCM), an indispensable part of herbal medicine, has been used for treating many diseases and/or symptoms for thousands of years. As we know, the main active components of TCM can account for its therapeutic effects. However, rational use of TCM faces a series of obstacles due to a large diversity of species and inaccurate knowledge of the active components. In recent years, more and more applications of new technologies or methodologies for investigating the active components of TCM have provided us with much additional information on active substances. Pharmacokinetics is an effective tool which can be used to investigate the many components of TCM. A pharmacokinetics approach reveals the dynamic processes of active components in vivo, including their absorption, distribution, metabolism, and excretion which offer guidance for clinical rational uses of TCM. Therefore, the objective of this paper is to review the current status of TCM, application of pharmacokinetics in investigating TCM, and emerging trends.

Graphical abstract: Recent advances in pharmacokinetics approach for herbal medicine

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Article information


Submitted
25 Feb 2017
Accepted
19 May 2017
First published
01 Jun 2017

This article is Open Access

RSC Adv., 2017,7, 28876-28888
Article type
Review Article

Recent advances in pharmacokinetics approach for herbal medicine

K. Zhang, G. Yan, A. Zhang, H. Sun and X. Wang, RSC Adv., 2017, 7, 28876
DOI: 10.1039/C7RA02369C

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