Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 12, 2017
Previous Article Next Article

New protocols to access imidazoles and their ring fused analogues: synthesis from N-propargylamines

Author affiliations

Abstract

Imidazole and its derivatives are privileged N-heterocyclic structures present in various natural products and synthetic pharmaceuticals. Despite the numerous methods that have been developed for the synthesis of imidazole cores, it is still challenging to readily achieve high efficiency and regioselectivity in imidazole synthesis. Therefore, synthesis of these compounds using new protocols is always interesting. In this study we discuss the most representative and interesting reports on the synthesis of imidazoles and their fused analogues from N-propargylamines. Mechanistic aspects of the reactions are considered and discussed in detail.

Graphical abstract: New protocols to access imidazoles and their ring fused analogues: synthesis from N-propargylamines

Back to tab navigation

Article information


Submitted
25 Oct 2016
Accepted
02 Jan 2017
First published
20 Jan 2017

This article is Open Access

RSC Adv., 2017,7, 7079-7091
Article type
Review Article

New protocols to access imidazoles and their ring fused analogues: synthesis from N-propargylamines

E. Vessally, S. Soleimani-Amiri, A. Hosseinian, L. Edjlali and A. Bekhradnia, RSC Adv., 2017, 7, 7079
DOI: 10.1039/C6RA25816F

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.

Reproduced material should be attributed as follows:

  • For reproduction of material from NJC:
    [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
  • For reproduction of material from PCCP:
    [Original citation] - Published by the PCCP Owner Societies.
  • For reproduction of material from PPS:
    [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
  • For reproduction of material from all other RSC journals:
    [Original citation] - Published by The Royal Society of Chemistry.

Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.


Social activity

Search articles by author

Spotlight

Advertisements