Jump to main content
Jump to site search

Issue 11, 2017
Previous Article Next Article

Cancer nanomedicine: from PDGF targeted drug delivery

Author affiliations


An innovative approach for the distinctively efficient action of smart targeted drug delivery to a specific cell type is obtained through the modification of the surface of nanoparticles. Specifically, the work identifies a cell surface receptor targeting drug delivery nanosystem based on mesoporous silica loaded with the anticancer drug cisplatin (cis-DDP) and poly-acrylic acid (PAA). A specific target is the PDGF receptors expressed in cervical cancer cells, thus making the PAA functionalized nanocomposite a suitable and promising nano-medicine for the targeting of PDGF-overexpressing cancers in the near future.

Graphical abstract: Cancer nanomedicine: from PDGF targeted drug delivery

Back to tab navigation

Supplementary files

Publication details

The article was received on 31 Jul 2017, accepted on 28 Sep 2017 and first published on 28 Sep 2017

Article type: Research Article
DOI: 10.1039/C7MD00391A
Med. Chem. Commun., 2017,8, 2055-2059

  •   Request permissions

    Cancer nanomedicine: from PDGF targeted drug delivery

    C. Rejeeth, R. Vivek, V. NipunBabu, A. Sharma, X. Ding and K. Qian, Med. Chem. Commun., 2017, 8, 2055
    DOI: 10.1039/C7MD00391A

Search articles by author