Jump to main content
Jump to site search

Issue 3, 2017
Previous Article Next Article

Surface acoustic wave enabled pipette on a chip

Author affiliations

Abstract

Mono-disperse droplet formation in microfluidic devices allows the rapid production of thousands of identical droplets and has enabled a wide range of chemical and biological studies through repeat tests performed at pico-to-nanoliter volume samples. However, it is exactly this efficiency of production which has hindered the ability to carefully control the location and quantity of the distribution of various samples on a chip – the key requirement for replicating micro well plate based high throughput screening in vastly reduced volumetric scales. To address this need, here, we present a programmable microfluidic chip capable of pipetting samples from mobile droplets with high accuracy using a non-contact approach. Pipette on a chip (PoaCH) system selectively ejects (pipettes) part of a droplet into a customizable reaction chamber using surface acoustic waves (SAWs). Droplet pipetting is shown to range from as low as 150 pL up to 850 pL with precision down to tens of picoliters. PoaCH offers ease of integration with existing lab on a chip systems as well as a robust and contamination-free droplet manipulation technique in closed microchannels enabling potential implementation in screening and other studies.

Graphical abstract: Surface acoustic wave enabled pipette on a chip

Back to tab navigation

Supplementary files

Article information


Submitted
24 Oct 2016
Accepted
14 Dec 2016
First published
14 Dec 2016

Lab Chip, 2017,17, 438-447
Article type
Paper

Surface acoustic wave enabled pipette on a chip

M. Sesen, C. Devendran, S. Malikides, T. Alan and A. Neild, Lab Chip, 2017, 17, 438
DOI: 10.1039/C6LC01318J

Social activity

Search articles by author

Spotlight

Advertisements