Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 11, 2017
Previous Article Next Article

Enzyme–MOF (metal–organic framework) composites

Author affiliations

Abstract

The ex vivo application of enzymes in various processes, especially via enzyme immobilization techniques, has been extensively studied in recent years in order to enhance the recyclability of enzymes, to minimize enzyme contamination in the product, and to explore novel horizons for enzymes in biomedical applications. Possessing remarkable amenability in structural design of the frameworks as well as almost unparalelled surface tunability, Metal–Organic Frameworks (MOFs) have been gaining popularity as candidates for enzyme immobilization platforms. Many MOF–enzyme composites have achieved unprecedented results, far outperforming free enzymes in many aspects. This review summarizes recent developments of MOF–enzyme composites with special emphasis on preparative techniques and the synergistic effects of enzymes and MOFs. The applications of MOF–enzyme composites, primarily in transferation, catalysis and sensing, are presented as well. The enhancement of enzymatic activity of the composites over free enzymes in biologically incompatible conditions is emphasized in many cases.

Graphical abstract: Enzyme–MOF (metal–organic framework) composites

Back to tab navigation

Article information


Submitted
25 Jan 2017
First published
28 Apr 2017

Chem. Soc. Rev., 2017,46, 3386-3401
Article type
Review Article

Enzyme–MOF (metal–organic framework) composites

X. Lian, Y. Fang, E. Joseph, Q. Wang, J. Li, S. Banerjee, C. Lollar, X. Wang and H. Zhou, Chem. Soc. Rev., 2017, 46, 3386
DOI: 10.1039/C7CS00058H

Social activity

Search articles by author

Spotlight

Advertisements