Issue 10, 2017

Biocatalysis engineering: the big picture

Abstract

In this tutorial review we describe a holistic approach to the invention, development and optimisation of biotransformations utilising isolated enzymes. Increasing attention to applied biocatalysis is motivated by its numerous economic and environmental benefits. Biocatalysis engineering concerns the development of enzymatic systems as a whole, which entails engineering its different components: substrate engineering, medium engineering, protein (enzyme) engineering, biocatalyst (formulation) engineering, biocatalytic cascade engineering and reactor engineering.

Graphical abstract: Biocatalysis engineering: the big picture

  • This article is part of the themed collection: Primer

Supplementary files

Article information

Article type
Tutorial Review
Submitted
28 Nov 2016
First published
13 Mar 2017

Chem. Soc. Rev., 2017,46, 2678-2691

Biocatalysis engineering: the big picture

R. A. Sheldon and P. C. Pereira, Chem. Soc. Rev., 2017, 46, 2678 DOI: 10.1039/C6CS00854B

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