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Issue 22, 2017
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Multiplexed photoluminescent sensors: towards improved disease diagnostics

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Abstract

The ability to simultaneously monitor multiple analytes in, for example, a single microplate well, is important for both basic research and clinical applications. In particular, for disease diagnosis there is a growing awareness that determination of a single disease biomarker is insufficient to pathologically confirm a disease state. Consequently, much recent literature has been directed towards the development of multiplexed photoluminescent sensors which can simultaneously detect multiple and diverse biomarkers that exist in a homogenous solution or a single cell, accelerating the progress towards precise disease diagnosis. This tutorial review highlights a selection of recent contributions towards this emerging interdisciplinary field that incorporates chemistry, chemical biology, materials sciences and medical sciences.

Graphical abstract: Multiplexed photoluminescent sensors: towards improved disease diagnostics

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Article information


Submitted
01 Jun 2017
First published
25 Aug 2017

This article is Open Access

Chem. Soc. Rev., 2017,46, 6687-6696
Article type
Tutorial Review

Multiplexed photoluminescent sensors: towards improved disease diagnostics

X. He, X. Hu, T. D. James, J. Yoon and H. Tian, Chem. Soc. Rev., 2017, 46, 6687
DOI: 10.1039/C6CS00778C

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    [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
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    [Original citation] - Published by The Royal Society of Chemistry.

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