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Issue 97, 2017
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Fluorous photosensitizers enhance photodynamic therapy with perfluorocarbon nanoemulsions

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Abstract

Photodynamic therapy (PDT) requires a photosensitizer, light, and oxygen to induce cell death. The majority of efforts to advance PDT focus only on the first two components. Here, we employ perfluorocarbon nanoemulsions to simultaneously deliver oxygen and a photosensitizer. We find that the implementation of fluorous soluble photosensitizers enhances the efficacy of PDT.

Graphical abstract: Fluorous photosensitizers enhance photodynamic therapy with perfluorocarbon nanoemulsions

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Supplementary files

Article information


Submitted
08 Sep 2017
Accepted
13 Nov 2017
First published
22 Nov 2017

Chem. Commun., 2017,53, 13043-13046
Article type
Communication

Fluorous photosensitizers enhance photodynamic therapy with perfluorocarbon nanoemulsions

R. A. Day, D. A. Estabrook, J. K. Logan and E. M. Sletten, Chem. Commun., 2017, 53, 13043
DOI: 10.1039/C7CC07038A

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