Issue 78, 2017

Syntheses and effectiveness of functional peptide-based RAFT agents

Abstract

In this study, a series of functional peptide-based RAFT agents were designed and synthesized by the solid-phase supported peptide synthesis method. These novel RAFT agents have enabled chemists to make well-defined peptide–polymer conjugates with complicated topological structures. Additionally, our results have shown an unexpected reaction that takes place during these syntheses, and the conversion of a nitrile group to a carboxamide group has been evidently elucidated and unambiguously confirmed.

Graphical abstract: Syntheses and effectiveness of functional peptide-based RAFT agents

Supplementary files

Article information

Article type
Communication
Submitted
10 Jul 2017
Accepted
30 Aug 2017
First published
30 Aug 2017

Chem. Commun., 2017,53, 10776-10779

Syntheses and effectiveness of functional peptide-based RAFT agents

C. Chen, F. Kong, X. Wei and S. H. Thang, Chem. Commun., 2017, 53, 10776 DOI: 10.1039/C7CC05316A

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