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Abstract | Cited by

We have developed an efficient chemical system that allows quantification of bacterial ribosomes by fluorescence-based analysis. The key component in the system is the exciton-controlled fluorescent RNA aptamer, which recognizes neomycin B. The intensity of fluorescence from such a ribosome-sensing system increased drastically in the presence of Escherichia coli.

Graphical abstract: Fluorescence-switching RNA for detection of bacterial ribosomes

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