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Issue 66, 2017
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Moisture resistant and biofriendly CD-MOF nanoparticles obtained via cholesterol shielding

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Abstract

A facile and one step-method was developed to enhance the water stability of CD-MOF nanoparticles through surface modification with cholesterol. CD-MOFs were able to maintain their cubic crystalline structures even after 24 h of incubation, well tolerated in vivo and could increase up to 4 times the blood half-life of DOX.

Graphical abstract: Moisture resistant and biofriendly CD-MOF nanoparticles obtained via cholesterol shielding

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Article information


Submitted
04 May 2017
Accepted
26 Jul 2017
First published
26 Jul 2017

Chem. Commun., 2017,53, 9246-9249
Article type
Communication

Moisture resistant and biofriendly CD-MOF nanoparticles obtained via cholesterol shielding

V. Singh, T. Guo, H. Xu, L. Wu, J. Gu, C. Wu, R. Gref and J. Zhang, Chem. Commun., 2017, 53, 9246
DOI: 10.1039/C7CC03471G

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