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Issue 53, 2017
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Cell-sized mechanosensitive and biosensing compartment programmed with DNA

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Abstract

The bottom-up construction of cell-sized compartments programmed with DNA that are capable of sensing the chemical and physical environment remains challenging in synthetic cell engineering. Here, we construct mechanosensitive liposomes with biosensing capability by expressing the E. coli channel MscL and a calcium biosensor using cell-free expression.

Graphical abstract: Cell-sized mechanosensitive and biosensing compartment programmed with DNA

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Article information


Submitted
04 May 2017
Accepted
12 May 2017
First published
12 May 2017

Chem. Commun., 2017,53, 7349-7352
Article type
Communication

Cell-sized mechanosensitive and biosensing compartment programmed with DNA

S. Majumder, J. Garamella, Y. Wang, M. DeNies, V. Noireaux and A. P. Liu, Chem. Commun., 2017, 53, 7349
DOI: 10.1039/C7CC03455E

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