Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 46, 2017
Previous Article Next Article

A deciduous directing group approach for the addition of aryl and vinyl nucleophiles to maleimides

Author affiliations

Abstract

A Rh(III)-catalyzed C–H activation followed by conjugate addition to maleimides, using carboxylic acid as a traceless/deciduous directing group, to formally furnish a Csp2–Csp3 bond is presented. For the first time, derivatives of acrylic acid have been shown as surrogates for the unstable and expensive alkenyl boronic acids.

Graphical abstract: A deciduous directing group approach for the addition of aryl and vinyl nucleophiles to maleimides

Back to tab navigation

Supplementary files

Article information


Submitted
28 Mar 2017
Accepted
15 May 2017
First published
15 May 2017

Chem. Commun., 2017,53, 6251-6254
Article type
Communication

A deciduous directing group approach for the addition of aryl and vinyl nucleophiles to maleimides

K. R. Bettadapur, V. Lanke and K. R. Prabhu, Chem. Commun., 2017, 53, 6251
DOI: 10.1039/C7CC02392H

Social activity

Search articles by author

Spotlight

Advertisements