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Issue 32, 2017
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An endoplasmic reticulum-selective ratiometric fluorescent probe for imaging a copper pool

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Abstract

Hydrazide-linked naphthalimides undergo copper ion-selective hydrolysis with concomitant ratiometric fluorescence change. In addition, probe 1 is biocompatible and mainly localized to the endoplasmic reticulum (ER) in live HeLa cells. It thus can be used for imaging copper accumulation in the ER of live cells, as implied in copper-overloaded situations.

Graphical abstract: An endoplasmic reticulum-selective ratiometric fluorescent probe for imaging a copper pool

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Publication details

The article was received on 23 Feb 2017, accepted on 27 Mar 2017 and first published on 28 Mar 2017


Article type: Communication
DOI: 10.1039/C7CC01430A
Chem. Commun., 2017,53, 4457-4460

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    An endoplasmic reticulum-selective ratiometric fluorescent probe for imaging a copper pool

    S. Y. Park, W. Kim, S. Park, J. Han, J. Lee, C. Kang and M. H. Lee, Chem. Commun., 2017, 53, 4457
    DOI: 10.1039/C7CC01430A

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