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Issue 34, 2017
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One-pot synthesis of thiazino[2,3,4-hi]indole derivatives through a tandem oxidative coupling/heteroannulation process

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Abstract

A novel and expedient one-pot synthesis of thiazino[2,3,4-hi]indole derivatives from o-haloaryl enamines and o-bromothiophenols has been developed. The tandem oxidative coupling/heteroannulation reactions exhibit high selectivity and good efficiency. The polycyclic heterocyclic products obtained might be useful in medicinal chemistry and materials science.

Graphical abstract: One-pot synthesis of thiazino[2,3,4-hi]indole derivatives through a tandem oxidative coupling/heteroannulation process

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Article information


Submitted
09 Feb 2017
Accepted
01 Apr 2017
First published
04 Apr 2017

Chem. Commun., 2017,53, 4718-4721
Article type
Communication

One-pot synthesis of thiazino[2,3,4-hi]indole derivatives through a tandem oxidative coupling/heteroannulation process

X. Mao, T. Tong, S. Fan, L. Fang, J. Wu, X. Wang, H. Kang and X. Lv, Chem. Commun., 2017, 53, 4718
DOI: 10.1039/C7CC00992E

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