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Issue 13, 2017
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Self-assembled lipoprotein based gold nanoparticles for detection and photothermal disaggregation of β-amyloid aggregates

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Abstract

We present a reconstituted lipoprotein-based nanoparticle platform comprising a curcumin fluorescent motif and an NIR responsive gold core. This multifunctional nanosystem is successfully used for aggregation-dependent fluorescence detection and photothermal disassembly of insoluble amyloid aggregates.

Graphical abstract: Self-assembled lipoprotein based gold nanoparticles for detection and photothermal disaggregation of β-amyloid aggregates

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Supplementary files

Article information


Submitted
14 Nov 2016
Accepted
10 Jan 2017
First published
10 Jan 2017

Chem. Commun., 2017,53, 2102-2105
Article type
Communication

Self-assembled lipoprotein based gold nanoparticles for detection and photothermal disaggregation of β-amyloid aggregates

P. A. T. Martins, S. Alsaiari, K. Julfakyan, Z. Nie and N. M. Khashab, Chem. Commun., 2017, 53, 2102
DOI: 10.1039/C6CC09085K

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