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Issue 3, 2017
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An efficient two-photon fluorescent probe for human NAD(P)H:quinone oxidoreductase (hNQO1) detection and imaging in tumor cells

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Abstract

A new quinone propionic acid locked TP fluorophore which can be used for human NAD(P)H:quinone oxidoreductase (hNQO1) detection was developed. The probe, TPQ, which displays high selectivity and anti-interference ability, was successfully applied to endogenous hNQO1 imaging and for the identification of different cancer cells.

Graphical abstract: An efficient two-photon fluorescent probe for human NAD(P)H:quinone oxidoreductase (hNQO1) detection and imaging in tumor cells

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Supplementary files

Article information


Submitted
10 Nov 2016
Accepted
05 Dec 2016
First published
05 Dec 2016

Chem. Commun., 2017,53, 525-528
Article type
Communication

An efficient two-photon fluorescent probe for human NAD(P)H:quinone oxidoreductase (hNQO1) detection and imaging in tumor cells

N. Kwon, M. K. Cho, S. J. Park, D. Kim, S. Nam, L. Cui, H. M. Kim and J. Yoon, Chem. Commun., 2017, 53, 525
DOI: 10.1039/C6CC08971B

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