Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 5, 2017
Previous Article Next Article

A Trp-BODIPY cyclic peptide for fluorescence labelling of apoptotic bodies

Author affiliations

Abstract

The rational design and synthesis of a Trp-BODIPY cyclic peptide for the fluorescent labelling of apoptotic bodies is described. Affinity assays, confocal microscopy and flow cytometry analysis confirmed the binding of the peptide to negatively-charged phospholipids associated with apoptosis, and its applicability for the detection and characterisation of subcellular structures released by apoptotic cells.

Graphical abstract: A Trp-BODIPY cyclic peptide for fluorescence labelling of apoptotic bodies

Back to tab navigation

Supplementary files

Article information


Submitted
28 Sep 2016
Accepted
13 Dec 2016
First published
15 Dec 2016

Chem. Commun., 2017,53, 945-948
Article type
Communication

A Trp-BODIPY cyclic peptide for fluorescence labelling of apoptotic bodies

R. Subiros-Funosas, L. Mendive-Tapia, J. Sot, J. D. Pound, N. Barth, Y. Varela, F. M. Goñi, M. Paterson, C. D. Gregory, F. Albericio, I. Dransfield, R. Lavilla and M. Vendrell, Chem. Commun., 2017, 53, 945
DOI: 10.1039/C6CC07879F

Social activity

Search articles by author

Spotlight

Advertisements