Issue 44, 2016

Theranostic body fluid cleansing: rationally designed magnetic particles enable capturing and detection of bacterial pathogens

Abstract

We report on theoretical and experimental considerations on bacteria capturing and enrichment via magnetic separation enabling integrated diagnosis and treatment of blood stream infections. We show optimization of carrier-pathogen interactions based on a mathematical model followed by an experimental proof-of-concept study along with investigations on the process safety.

Graphical abstract: Theranostic body fluid cleansing: rationally designed magnetic particles enable capturing and detection of bacterial pathogens

Supplementary files

Article information

Article type
Communication
Submitted
20 May 2016
Accepted
15 Oct 2016
First published
17 Oct 2016

J. Mater. Chem. B, 2016,4, 7080-7086

Theranostic body fluid cleansing: rationally designed magnetic particles enable capturing and detection of bacterial pathogens

M. Lattuada, Q. Ren, F. Zuber, M. Galli, N. Bohmer, M. T. Matter, A. Wichser, S. Bertazzo, G. B. Pier and I. K. Herrmann, J. Mater. Chem. B, 2016, 4, 7080 DOI: 10.1039/C6TB01272H

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