Issue 2, 2016

Pot economy and one-pot synthesis


The one-pot synthesis of a target molecule in the same reaction vessel is widely considered to be an efficient approach in synthetic organic chemistry. In this review, the characteristics and limitations of various one-pot syntheses of biologically active molecules are explained, primarily involving organocatalytic methods as key tactics. Besides catalysis, the pot-economy concepts presented herein are also applicable to organometallic and organic reaction methods in general.

Graphical abstract: Pot economy and one-pot synthesis

Article information

Article type
07 Aug 2015
26 Nov 2015
First published
06 Jan 2016
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY license

Chem. Sci., 2016,7, 866-880

Pot economy and one-pot synthesis

Y. Hayashi, Chem. Sci., 2016, 7, 866 DOI: 10.1039/C5SC02913A

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