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Issue 2, 2016
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Continuous photochemistry: the flow synthesis of ibuprofen via a photo-Favorskii rearrangement

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Abstract

A new enabling technology for performing photochemical reactions in a continuous fashion is presented. This photo-reactor is compatible with existing flow systems and can be furthermore linked to a photo-spectrometer in order to allow for real time analysis of photochemical reactions. In this communication we wish to report the profiling of this system and its application to the continuous synthesis of ibuprofen based on a photo-Favorskii rearrangement reaction of a readily available α-chloropropiophenone precursor.

Graphical abstract: Continuous photochemistry: the flow synthesis of ibuprofen via a photo-Favorskii rearrangement

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Supplementary files

Article information


Submitted
21 Sep 2015
Accepted
19 Oct 2015
First published
04 Nov 2015

React. Chem. Eng., 2016,1, 147-150
Article type
Communication
Author version available

Continuous photochemistry: the flow synthesis of ibuprofen via a photo-Favorskii rearrangement

M. Baumann and I. R. Baxendale, React. Chem. Eng., 2016, 1, 147
DOI: 10.1039/C5RE00037H

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