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Issue 115, 2016, Issue in Progress
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Effects of cytotoxicity of erythromycin on PAH-degrading strains and degrading efficiency

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Abstract

The toxicity and degradation effects of erythromycin on a phenanthrene degrading strain of Sphingomonas sp. GY2B and a pyrene degrading strain of Mycobacterium gilvum CP13 were investigated. The minimum inhibitory concentration (MIC) of erythromycin to GY2B was 0.25 mg L−1, but the MIC of erythromycin to CP13 was 16 mg L−1. Total superoxide dismutase (SOD) activity and lactate dehydrogenase (LDH) activity were significantly reduced when the erythromycin concentration exceeded the MIC. Erythromycin also reduced the growth of the strains and the biodegradation of polycyclic aromatic hydrocarbons (PAHs). Addition of erythromycin decreased GY2B phenanthrene removal efficiency by 0.81–86.03% compared to the control. Erythromycin also reduced CP13 pyrene degradation. The lowest pyrene removal efficiency was 10.78% when the erythromycin concentration was 256 mg L−1. The toxicity of erythromycin inhibited the growth of both GY2B and CP13.

Graphical abstract: Effects of cytotoxicity of erythromycin on PAH-degrading strains and degrading efficiency

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Publication details

The article was received on 27 Sep 2016, accepted on 23 Nov 2016 and first published on 24 Nov 2016


Article type: Paper
DOI: 10.1039/C6RA23957A
Citation: RSC Adv., 2016,6, 114396-114404

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    Effects of cytotoxicity of erythromycin on PAH-degrading strains and degrading efficiency

    Y. Huang, C. Yang, Y. Li, C. Guo and Z. Dang, RSC Adv., 2016, 6, 114396
    DOI: 10.1039/C6RA23957A

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