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Here we present the fabrication of bifunctional nanocapsules via cation (Ca2+/Gd3+) induced self-assembly of partially hydrolysed α-lactalbumin. The prepared nanospheres, encapsulated with photosensitizer (Rose Bengal) and Gd3+ ion, show great potentials for magnetic resonance imaging and photodynamic therapy with a target-specific manner.

Graphical abstract: Bifunctional nanocapsules for magnetic resonance imaging and photodynamic therapy

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