Issue 71, 2016, Issue in Progress

Pyrene appended thymine derivative for selective turn-on fluorescence sensing of uric acid in live cells

Abstract

A new ‘turn-ON’ fluorescent probe, pyrene appended thymine acetamide (PTA), with high sensitivity and selectivity for the detection of uric acid (UA) was developed and first time imaging of uric acid in living cells in water was achieved. 1H NMR and density functional studies on the system have been carried out to determine the nature of the interaction between probe PTA and UA.

Graphical abstract: Pyrene appended thymine derivative for selective turn-on fluorescence sensing of uric acid in live cells

Supplementary files

Article information

Article type
Communication
Submitted
20 Jun 2016
Accepted
07 Jul 2016
First published
13 Jul 2016

RSC Adv., 2016,6, 66774-66778

Pyrene appended thymine derivative for selective turn-on fluorescence sensing of uric acid in live cells

P. Sahoo, H. S. Sarkar, S. Das, K. Maiti, M. R. Uddin and S. Mandal, RSC Adv., 2016, 6, 66774 DOI: 10.1039/C6RA15980J

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