Gold-catalyzed formation of indole derivatives from 2-alkynyl arylazides and oxygen-containing heterocycles

Xiaoxiang Zhang; Xiaoping Sun; Hui Fan; Chang Lyu; Ping Li; Haifei Zhang; Weidong Rao

doi:10.1039/C6RA09761H

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Gold-catalyzed formation of indole derivatives from 2-alkynyl arylazides and oxygen-containing heterocycles†

Xiaoxiang Zhang,*^a Xiaoping Sun,^a Hui Fan,^b Chang Lyu,^a Ping Li,^a Haifei Zhang^a and Weidong Rao*^a

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* Corresponding authors

^a Jiangsu Key Lab of Biomass-Based Green Fuels and Chemicals, College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China
E-mail: zhangxiaoxiang@njfu.edu.cn, weidong@njfu.edu.cn

^b School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China

Abstract

A novel method for the formation of indole derivatives via gold-catalyzed tandem reactions of 2-alkynyl arylazides and oxygen-containing heterocycles has been developed. A variety of indole derivatives were prepared under mild reaction conditions.

This article is part of the themed collections: Elegant Synthetic Routes to Indole Derivatives and Editors’ collection: Catalytic Organic Transformations

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Article information

DOI: https://doi.org/10.1039/C6RA09761H
Article type: Communication
Submitted: 15 Apr 2016
Accepted: 02 Jun 2016
First published: 07 Jun 2016

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RSC Adv., 2016,6, 56319-56322

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Gold-catalyzed formation of indole derivatives from 2-alkynyl arylazides and oxygen-containing heterocycles

X. Zhang, X. Sun, H. Fan, C. Lyu, P. Li, H. Zhang and W. Rao, RSC Adv., 2016, 6, 56319 DOI: 10.1039/C6RA09761H

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Gold-catalyzed formation of indole derivatives from 2-alkynyl arylazides and oxygen-containing heterocycles†

Abstract

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Gold-catalyzed formation of indole derivatives from 2-alkynyl arylazides and oxygen-containing heterocycles

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