Issue 63, 2016
From the journal:

RSC Advances

A facile access to cis-dihydrofurobenzofuran from 2-(2,5-dihydro-furan-2-yl)-phenol†

Xiao-Hui Hu,a   Xiao-Qiu Pu,a   Rui Liu,a   Chun-Xiao Cui,a   Jun Yang*b  and  Xian-Jin Yang*ab  

* Corresponding authors

a Key Lab for Advanced Material & Institute of Fine Chemicals, East China University of Science and Technology, 130 Meilong Road, Shanghai 2002 31, China
E-mail: yxj@ecust.edu.cn

b Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Science, 345 Ling-Ling Road, Shanghai 200232, China

Abstract

A facile access to cis-dihydrofurobenzofuran from a Pd-catalyzed intramolecular oxidative C–O bond formation of 2-(2,5-dihydro-furan-2-yl)-phenol is reported. The combined use of Pd(OAc)2 as catalyst, acetonitrile as solvent and AgOAc or air as oxidant affords cis-dihydrofurobenzofurans in good (up to 83%) yields.

Graphical abstract: A facile access to cis-dihydrofurobenzofuran from 2-(2,5-dihydro-furan-2-yl)-phenol

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Article information

DOI
https://doi.org/10.1039/C6RA06840E
Article type
Communication
Submitted
15 Mar 2016
Accepted
27 May 2016
First published
03 Jun 2016

RSC Adv., 2016,6, 58613-58616

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A facile access to cis-dihydrofurobenzofuran from 2-(2,5-dihydro-furan-2-yl)-phenol

X. Hu, X. Pu, R. Liu, C. Cui, J. Yang and X. Yang, RSC Adv., 2016, 6, 58613 DOI: 10.1039/C6RA06840E

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