Issue 59, 2016, Issue in Progress
From the journal:

RSC Advances

In situ generation of dihydropyridine for the enantioselective transfer hydrogenation of 1,4-benzoxazines†

Alexandre Aillerie,a   Cyrille Gosset,a   Clément Dumont,a   Valentin Skrzypczak,a   Philippe Champetter,a   Sylvain Pellegrini,a   Till Bousquet*a  and  Lydie Pélinski*a  

* Corresponding authors

a Université de Lille, CNRS, ENSCL, UMR 8181 – UCCS – Unité de Catalyse et de Chimie du Solide, F-59000 Lille, France
E-mail: till.bousquet@univ-lille1.fr, lydie.pelinski@univ-lille1.fr

Abstract

A new strategy for the enantioselective transfer hydrogenation of benzoxazines involving an in situ generation of Hantzsch ester has been developed. Dihydroadducts were isolated in good yields (75–99%) and enantioselectivities (89–96% ee).

Graphical abstract: In situ generation of dihydropyridine for the enantioselective transfer hydrogenation of 1,4-benzoxazines

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C6RA04930C
Article type
Communication
Submitted
24 Feb 2016
Accepted
25 May 2016
First published
27 May 2016

RSC Adv., 2016,6, 54185-54188

Permissions

Request permissions

In situ generation of dihydropyridine for the enantioselective transfer hydrogenation of 1,4-benzoxazines

A. Aillerie, C. Gosset, C. Dumont, V. Skrzypczak, P. Champetter, S. Pellegrini, T. Bousquet and L. Pélinski, RSC Adv., 2016, 6, 54185 DOI: 10.1039/C6RA04930C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements