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Issue 38, 2016
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Diselenide-based probe for the selective imaging of hypochlorite in living cancer cells

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Abstract

A non-traditional and robust probe skeleton was derivatized for chemosensing applications to investigate a potential novel mode of hypochlorite detection. The BDPP-DSe probe gave a ∼180-fold “turn-on” response to hypochlorite. Confocal fluorescence imaging demonstrated detection of hypochlorite in living cells and cell membrane permeability.

Graphical abstract: Diselenide-based probe for the selective imaging of hypochlorite in living cancer cells

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Supplementary files

Article information


Submitted
17 Feb 2016
Accepted
22 Mar 2016
First published
24 Mar 2016

RSC Adv., 2016,6, 32013-32017
Article type
Communication

Diselenide-based probe for the selective imaging of hypochlorite in living cancer cells

Y. Kim, M. Choi, S. T. Manjare, S. Jon and D. G. Churchill, RSC Adv., 2016, 6, 32013
DOI: 10.1039/C6RA04257K

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