Anirban Kayet, Arghya Ganguly and Tanmaya Pathak
RSC Adv., 2016,6, 7977-7981
DOI:
10.1039/C5RA25942H,
Communication
1,5-Disubstituted 1,2,3-triazole (1,5-DT) linked disaccharides have been synthesized from stable building blocks having both vinyl sulfone and azido groups using aqueous ionic-liquid media. These building blocks containing secondary azido groups do not undergo self-coupling but react with the externally delivered primary azidosugars. The disaccharides are coupled with appropriate building blocks for the preparation of the first ever 1,5-DT linked- and 1,4-/1,5-DT-linked trisaccharides using aqueous ionic-liquid and water–butanol based “click” chemistry, respectively.