Issue 17, 2016

Tuning the nitric oxide release from CPO-27 MOFs


Nitric oxide (NO) storage and release measurements have been recorded for Ni-doped CPO-27 (Mg) and CPO-27 (Zn), and the biological effect of the released NO was assessed in porcine coronary artery relaxation tests. The results indicate that the doping strategy leads to increased levels of NO storage and delivery compared to the parent materials and that the NO dosage and biological response can be tuned via this approach to suit the requirements of particular applications.

Graphical abstract: Tuning the nitric oxide release from CPO-27 MOFs

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Article information

Article type
13 Nov 2015
17 Jan 2016
First published
26 Jan 2016
This article is Open Access
Creative Commons BY license

RSC Adv., 2016,6, 14059-14067

Author version available

Tuning the nitric oxide release from CPO-27 MOFs

D. Cattaneo, S. J. Warrender, M. J. Duncan, C. J. Kelsall, M. K. Doherty, P. D. Whitfield, I. L. Megson and R. E. Morris, RSC Adv., 2016, 6, 14059 DOI: 10.1039/C5RA24023A

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