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Issue 35, 2016
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Carbon nano onions cross the blood brain barrier

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Abstract

We show the crossing of small sized water soluble fluorescent carbon nano onion (wsCNO) through the blood brain barrier (BBB) in the Cerebral Autosomal-Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) murine model as well as in glioblastoma multiforme (GBM) induced mice. It is readily excreted from the body after a few days suggesting its possible use as cargo in drug delivery.

Graphical abstract: Carbon nano onions cross the blood brain barrier

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Article information


Submitted
08 Nov 2015
Accepted
16 Mar 2016
First published
17 Mar 2016

RSC Adv., 2016,6, 29779-29782
Article type
Communication

Carbon nano onions cross the blood brain barrier

B. Pakhira, M. Ghosh, A. Allam and S. Sarkar, RSC Adv., 2016, 6, 29779
DOI: 10.1039/C5RA23534K

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