Palladium-catalyzed ring contraction reaction of naphthoquinones upon reaction with alkynes†
Abstract
An unprecedented palladium catalysed ring contraction reaction of naphthoquinones with alkynes has been developed. A wide range of phthalides are synthesized in good to high yields and with high regioselectivities. These synthesized phthalides are versatile synthetic intermediates toward many other useful synthetic building blocks.
 
                



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