Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 27th March 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.

Issue 3, 2016
Previous Article Next Article

Pd(II)-catalyzed β-C–H arylation of O-methyl ketoximes with iodoarenes

Author affiliations


A Pd(II)-catalyzed selective β-arylation of O-methyl ketoximes was developed using iodoarenes as the coupling partners. This transformation has good functional group compatibility and can serve as a powerful synthetic tool for late-stage C–H arylation of complex compounds. Moreover, when employing 2-iodobenzoic acids as the substrates in this developed catalytic system, a type of unexpected five-membered lactones could be formed by tandem sp3 C–H arylation and oxygenation.

Graphical abstract: Pd(ii)-catalyzed β-C–H arylation of O-methyl ketoximes with iodoarenes

Back to tab navigation

Supplementary files

Publication details

The article was received on 24 Dec 2015, accepted on 20 Jan 2016 and first published on 21 Jan 2016

Article type: Research Article
DOI: 10.1039/C5QO00438A
Author version
Download author version (PDF)
Citation: Org. Chem. Front., 2016,3, 380-384

  •   Request permissions

    Pd(II)-catalyzed β-C–H arylation of O-methyl ketoximes with iodoarenes

    Y. Mu, X. Tan, Y. Zhang, X. Jing and Z. Shi, Org. Chem. Front., 2016, 3, 380
    DOI: 10.1039/C5QO00438A

Search articles by author