A transition-metal-free conversion of 2-arylindoles to 2-aminoarylphenones, using environmentally benign O2 as the sole oxidant, has been developed. This novel oxidative dearomatization process involves cleavage of both C–C and C–N bonds followed by new C–C and C–O bond formation. The C2 carbon of an indole scaffold was released in the form of CO2.
S. Luo, Z. Hu and Q. Zhu, Org. Chem. Front., 2016, 3, 364 DOI: 10.1039/C5QO00394F
To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.
If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.
If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.
Read more about how to correctly acknowledge RSC content.
Please wait while we load your content...
