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Issue 38, 2016
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Polyacrylamide backbones for polyvalent bioconjugates using “post-click” chemistry

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Abstract

This paper reports the synthesis and application of acrylamide-type neoglycoconjugates interacting with practical targets. Polymer backbones with acrylamide and acrylamide derivatives bearing alkyne groups were prepared using living radical polymerization. Oligosaccharides were introduced into the backbones using copper-catalysed azide–alkyne cycloaddition “post-click” chemistry.

Graphical abstract: Polyacrylamide backbones for polyvalent bioconjugates using “post-click” chemistry

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Publication details

The article was received on 25 May 2016, accepted on 10 Jul 2016 and first published on 26 Jul 2016


Article type: Communication
DOI: 10.1039/C6PY00904B
Citation: Polym. Chem., 2016,7, 5920-5924

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    Polyacrylamide backbones for polyvalent bioconjugates using “post-click” chemistry

    M. Nagao, Y. Kurebayashi, H. Seto, T. Takahashi, T. Suzuki, Y. Hoshino and Y. Miura, Polym. Chem., 2016, 7, 5920
    DOI: 10.1039/C6PY00904B

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