Cintia Anton-Torrecillas, Diego Felipe-Blanco and Jose C. Gonzalez-Gomez
Org. Biomol. Chem., 2016,14, 10620-10629
DOI:
10.1039/C6OB02103D,
Paper
Mildly basic aqueous conditions facilitated the tert-butyl peroxybenzoate (TBPB) mediated dehydrogenative addition of a range of ethers, including acetals, to diverse substituted 2-isocyanobiaryls. Mechanistic studies suggest that this radical cascade is an example of base promoted homolytic aromatic substitution (BHAS).