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Issue 39, 2016
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A practical oxidative C–H functionalization of N-carbamoyl tetrahydro-β-carbolines with diverse potassium trifluoroborates

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Abstract

A practical and mild metal-free oxidative C–H functionalization of N-carbamoyl tetrahydro-β-carbolines has been reported. This reaction has excellent functional group tolerance, and exhibits a broad range of potassium trifluoroborate components, allowing for the facile C–H functionalization of electronically varied N-carbamoyl THCs in high efficiency with excellent regioselectivity.

Graphical abstract: A practical oxidative C–H functionalization of N-carbamoyl tetrahydro-β-carbolines with diverse potassium trifluoroborates

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Publication details

The article was received on 29 May 2016, accepted on 15 Aug 2016 and first published on 19 Sep 2016


Article type: Paper
DOI: 10.1039/C6OB01171C
Citation: Org. Biomol. Chem., 2016,14, 9431-9438

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    A practical oxidative C–H functionalization of N-carbamoyl tetrahydro-β-carbolines with diverse potassium trifluoroborates

    Y. Sun, G. Wang, J. Chen, C. Liu, M. Cai, R. Zhu, H. Huang, W. Li and L. Liu, Org. Biomol. Chem., 2016, 14, 9431
    DOI: 10.1039/C6OB01171C

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