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Issue 39, 2016
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A practical oxidative C–H functionalization of N-carbamoyl tetrahydro-β-carbolines with diverse potassium trifluoroborates

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Abstract

A practical and mild metal-free oxidative C–H functionalization of N-carbamoyl tetrahydro-β-carbolines has been reported. This reaction has excellent functional group tolerance, and exhibits a broad range of potassium trifluoroborate components, allowing for the facile C–H functionalization of electronically varied N-carbamoyl THCs in high efficiency with excellent regioselectivity.

Graphical abstract: A practical oxidative C–H functionalization of N-carbamoyl tetrahydro-β-carbolines with diverse potassium trifluoroborates

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Supplementary files

Article information


Submitted
29 May 2016
Accepted
15 Aug 2016
First published
19 Sep 2016

Org. Biomol. Chem., 2016,14, 9431-9438
Article type
Paper

A practical oxidative C–H functionalization of N-carbamoyl tetrahydro-β-carbolines with diverse potassium trifluoroborates

Y. Sun, G. Wang, J. Chen, C. Liu, M. Cai, R. Zhu, H. Huang, W. Li and L. Liu, Org. Biomol. Chem., 2016, 14, 9431
DOI: 10.1039/C6OB01171C

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