Lenka Kubovičová, Kristýna Bürglová and Jan Hlaváč
Org. Biomol. Chem., 2016,14, 4824-4828
DOI:
10.1039/C6OB00737F,
Paper
An efficient method for removal of the hydrazine group from (hetero)aromatic substrates has been developed. It can be realized both on a solid support and in solution by synthesis employing a low concentration solution of trimethylsilanolate in tetrahydrofuran or N,N-dimethylformamide. For water-soluble substrates, the reaction can be performed in water, highlighting the eco-friendly attributes of this methodology.