Xiaowen Yang, Dimin Wu, Zhaohong Lu, Hongbin Sun and Ang Li
Org. Biomol. Chem., 2016,14, 5591-5594
DOI:
10.1039/C6OB00345A,
Communication
We report herein a protocol for preparing alkynes from alkenyl triflates. Stoichiometric LiCl promotes this transformation in DMF at ambient temperature. A range of terminal and internal alkynes were obtained smoothly. A one-pot procedure of alkyne formation/Cu-mediated Huisgen cycloaddition was developed, which may find use in synthesizing natural product-based probes.