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Issue 44, 2016
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Three-minute synthesis of sp3 nanocrystalline carbon dots as non-toxic fluorescent platforms for intracellular delivery

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Abstract

A one-pot, three-minute, gram-scale synthesis of novel sp3-nanocrystalline, water-soluble, and fluorescent carbon dots (FCDs), from simple and cheap sugar starting materials is described. Mechanism studies showed that NH2-FCD formation proceeds via a crucial imine intermediate derived from reaction between a sugar hemiacetal and an amine. Moreover, we successfully demonstrate the utility of lactose functionalized FCDots (Lac-FCDots) as non-toxic fluorescent intracellular delivery vehicles.

Graphical abstract: Three-minute synthesis of sp3 nanocrystalline carbon dots as non-toxic fluorescent platforms for intracellular delivery

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Supplementary files

Article information


Submitted
16 Sep 2016
Accepted
20 Oct 2016
First published
21 Oct 2016

This article is Open Access

Nanoscale, 2016,8, 18630-18634
Article type
Communication

Three-minute synthesis of sp3 nanocrystalline carbon dots as non-toxic fluorescent platforms for intracellular delivery

S. A. Hill, David. Benito-Alifonso, D. J. Morgan, S. A. Davis, M. Berry and M. C. Galan, Nanoscale, 2016, 8, 18630
DOI: 10.1039/C6NR07336K

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