Issue 5, 2016

Vibrational spectroscopy and imaging for concurrent cellular trafficking of co-localized doxorubicin and deuterated phospholipid vesicles

Abstract

Simultaneous tracking of nanoparticles and encapsulated payload is of great importance and visualizing their activity is arduous. Here we use vibrational spectroscopy to study the in vitro tracking of co-localized lipid nanoparticles and encapsulated drug employing a model system derived from doxorubicin-encapsulated deuterated phospholipid (dodecyl phosphocholine-d38) single tailed phospholipid vesicles.

Graphical abstract: Vibrational spectroscopy and imaging for concurrent cellular trafficking of co-localized doxorubicin and deuterated phospholipid vesicles

Supplementary files

Article information

Article type
Paper
Submitted
12 Nov 2015
Accepted
03 Jan 2016
First published
05 Jan 2016

Nanoscale, 2016,8, 2826-2831

Author version available

Vibrational spectroscopy and imaging for concurrent cellular trafficking of co-localized doxorubicin and deuterated phospholipid vesicles

S. K. Misra, P. Mukherjee, A. Ohoka, A. S. Schwartz-Duval, S. Tiwari, R. Bhargava and D. Pan, Nanoscale, 2016, 8, 2826 DOI: 10.1039/C5NR07975F

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